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Updated: Apr 13, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian
Yu Yang1, Jing Zhang2, Zhi-yu Han2
11] Department of Interventional Ultrasound, Chinese PLA General Hospital [2] Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University. (This study was performed at Chinese PLA General Hospital).
Abstract:
A total of 142 premenopausal women with symptomatic adenomyosis underwent ultrasound (US)-guided percutaneous microwave ablation (PMWA) at the Chinese PLA General Hospital. This study aimed to evaluate changes in serum pituitary, gonadal hormone and cancer antigen 125 (CA125) levels after US-guided PMWA. Therefore, estradiol (E2), follicle-stimulating hormone (FSH), prolactin (PRL) and CA125 levels were evaluated before ablation and at 3, 6, 9 and 12 months after ablation. No significant differences were observed in the E2 and FSH levels pre-ablation and during follow-up (E2: p=0.933, p=0.987, p=0.106, p=0.936; FSH: p=0.552, p=0.295, p=0.414, p=0.760). The mean absolute values of serum CA125 and PRL were significantly decreased at 3, 6, 9 and 12 months after ablation (CA125: p<0.001, p<0.001, p<0.001, p=0.003; PRL: p<0.001, p<0.001, p<0.001, p<0.001). A significant correlation between changes in CA125 levels and uterine volume was found (p<0.001). No evidence of a decline in ovarian function was observed after US-guided PMWA.
