Florid osseous dysplasia in Orientals

Area of Science:

• Oral and Maxillofacial Pathology
• Dental Radiology
• Skeletal Dysplasias

Background:

• Florid osseous dysplasia (FOD) is a condition characterized by multiple radiopaque cementum-like masses in the jaws.
• Historically, it has been described predominantly in middle-aged Black women, with varied nomenclature including gigantiform cementoma.
• This condition's prevalence and demographic distribution beyond the initially described population require further investigation.

Purpose of the Study:

• To document cases of florid osseous dysplasia in ethnic Chinese and Indian individuals.
• To expand the understanding of the demographic distribution of this condition.
• To contribute radiographic and histopathologic data to the existing literature on FOD.

Main Methods:

• Retrospective review of eight cases of florid osseous dysplasia in middle-aged, female ethnic Chinese individuals.
• Inclusion of one case in an Indian subject.
• Analysis based on radiographic and histopathologic findings.

Main Results:

• Documentation of nine cases of florid osseous dysplasia in non-Black populations.
• Estimated incidence of 0.01 cases per 100,000 population per year based on this series.
• Florid osseous dysplasia accounted for 11% of all cemental lesions in the study files.

Conclusions:

• Florid osseous dysplasia can occur in diverse ethnic groups, including ethnic Chinese and Indian individuals.
• The findings suggest a broader demographic prevalence than previously reported.
• Further research is warranted to fully elucidate the epidemiology and pathogenesis of florid osseous dysplasia.