Body composition among Sri Lankan infants by ¹⁸O dilution method and the validity of anthropometric equations to

Thushari Bandara1, Manjula Hettiarachchi2, Chandrani Liyanage3

  • 1Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. wvthush@yahoo.com.

BMC Pediatrics
|May 7, 2015
PubMed

Insights

Body composition in Sri Lankan infants is comparable to international standards. The Durnin & Wormsley skinfold equation is the most accurate for predicting body fat in this population, showing the least bias.

Area of Science:

  • Pediatrics
  • Human Nutrition
  • Anthropometry

Background:

  • Accurate body composition assessment is crucial for monitoring infant growth and nutritional status.
  • The (18)O dilution method offers a precise reference for measuring body composition.
  • Evaluating anthropometric prediction equations against reference methods is essential for their clinical applicability.

Purpose of the Study:

  • To measure Sri Lankan infant body composition using the (18)O dilution method.
  • To calculate infant body fat using established skinfold prediction equations.
  • To assess the accuracy of these skinfold equations for Sri Lankan infants compared to the (18)O dilution reference.

Main Methods:

  • A cross-sectional study involving 25 healthy, exclusively breast-fed infants.
  • Body composition measured via (18)O dilution.
  • Anthropometric measurements included weight, length, skinfold thickness, and mid-upper arm circumference.
  • Bland and Altman analysis compared anthropometric predictions to (18)O dilution values.

Main Results:

  • Infant body weight averaged 6.5 kg and length 64.7 cm.
  • (18)O dilution revealed mean total body water of 58.8%, fat-free mass of 4.6 kg, fat mass of 1.9 kg, and % fat mass of 29.5%.
  • Boys exhibited significantly higher total body water and fat-free mass than girls.
  • Most skinfold equations showed a bias dependent on % fat mass, unlike three specific equations (Bandana, Goran, Durnin & Wormsley).

Conclusions:

  • Sri Lankan infant body composition aligns with data from industrialized nations.
  • Common anthropometric equations demonstrate variable bias, influenced by body fat levels.
  • The Bandana, Goran, and Durnin & Wormsley equations exhibited constant bias.
  • The Durnin & Wormsley equation demonstrated the lowest bias and narrowest agreement limits against the (18)O dilution reference.
  • Equation accuracy can be influenced by infant gender.
Abstract