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Updated: Apr 12, 2026
Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases
Published on: November 8, 2024
Dimethylether treatment for condyloma acuminata in women
T L Gaydos1, H A Lambe, K Schwartz
1*Department of Obstetrics and Gynecology and Research Institute, St. Luke's Hospital, Bethlehem, PA.
Objective:
Our aim was to test a new cryosurgical wart treatment, dimethylether (Histofreezer), for clinical effi-cacy in newly diagnosed cases of genital warts.
Methods:
All patients of the gynecology clinic of a teaching hospital who were at least 12 years of age and who had between one and eight external genital warts were eligible. Treatment occurred at the initial visit and at follow-up visits at 2, 4, 6, and 8 weeks. If all warts were gone at any particular visit, the patient had completed the study and was not required to return.
Results:
In 14 of 15 patients [93%; 95% confidence interval (Cl), 81-100%], all warts resolved within the 8-week study period. This included 39 of 44 warts (89%; 95% Cl 80-98%). Most warts [35 of 44 (80%)] resolved within 4 weeks. One patient with five warts failed treatment. No known complications were seen. Condusion. Dimethylether (Histofreezer) is an effective cryosurgical treatment for genital warts.
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