Related Experiment Video
Updated: Apr 12, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
Evolving Gaussian Mixture Models with Splitting and Merging Mutation Operators
Thiago Ferreira Covões1, Eduardo Raul Hruschka2, Joydeep Ghosh3
1Department of Computer Science, University of São Paulo, São Carlos, Brazil tcovoes@icmc.usp.br.
Abstract:
This paper describes the evolutionary split and merge for expectation maximization (ESM-EM) algorithm and eight of its variants, which are based on the use of split and merge operations to evolve Gaussian mixture models. Asymptotic time complexity analysis shows that the proposed algorithms are competitive with the state-of-the-art genetic-based expectation maximization (GA-EM) algorithm. Experiments performed in 35 data sets showed that ESM-EM can be computationally more efficient than the widely used multiple runs of EM (for different numbers of components and initializations). Moreover, a variant of ESM-EM free from critical parameters was shown to be able to provide competitive results with GA-EM, even when GA-EM parameters were fine-tuned a priori.
More Related Videos
10:50Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
Published on: April 1, 2016
12:27Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
Published on: February 15, 2017
Related Concept Videos
Mutation, Gene Flow, and Genetic Drift
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Genetic Drift
¹H NMR: Complex Splitting
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied...
Mismatch Repair
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Point and Frameshift Mutations