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Updated: Apr 12, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Cooling rate effects on thermal, structural, and microstructural properties of bio-hydroxyapatite obtained from
Cristian F Ramirez-Gutierrez1, Anderzon F Palechor-Ocampo1, Sandra M Londoño-Restrepo1
1Posgrado en Ciencia e Ingeniería de Materiales, Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México Campus Juriquilla, Querétaro, Qro., México.
Abstract:
This article is focused on the study of cooling rate effects on the thermal, structural, and microstructural properties of hydroxyapatite (HAp) obtained from bovine bone. A three-step process was used to obtain BIO-HAp: hydrothermal, calcinations, and cooling. Calcined samples in a furnace and cooling in air (HAp-CAir), water (HAp-CW), and liquid nitrogen (HAp-CN2), as well as an air cooled sample inside the furnace (HAp-CFAir), were studied. According to this study, the low cooling rate that was achieved for air cooled samples inside the furnace produce single crystal BIO-HAp with better crystalline quality; other samples exhibited polycrystalline structures forming micron and submicron grains.
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