Related Experiment Video
Updated: Apr 12, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
EUS-directed transgastric ERCP for Roux-en-Y gastric bypass anatomy: a minimally invasive approach
Prashant Kedia1, Amy Tyberg1, Nikhil A Kumta1
1Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, New York, USA.
Background:
ERCP is challenging in patients with Roux-en-Y gastric bypass. Using EUS to gain access to the excluded stomach and subsequently performing transcutaneous ERCP was described recently.
Objective:
We describe our initial experience with an internal EUS-directed transgastric ERCP (EDGE) procedure by using a lumen-apposing metal stent (LAMS).
Design:
Single-center case series.
Setting:
Tertiary center with expertise in EUS-guided procedures.
Patients:
Five patients with Roux-en-Y gastric bypass underwent EDGE via a LAMS.
Interventions:
A linear echoendoscope was used to access the excluded stomach. A LAMS was deployed over a wire to create a gastrogastric or jejunogastric fistula. A duodenoscope was then passed through the LAMS and conventional ERCP was performed.
Main Outcome Measurements:
Technical and clinical success rates as well as adverse events.
Results:
EUS-guided creation of a gastrogastric or jejunogastric fistula via placement of a LAMS was successful in all cases (100%). The ability to perform ERCP through the fashioned fistula during the index procedure was successful in 3 of 5 cases (60%). Two LAMS dislodgments requiring restenting were observed. No major adverse events were observed. No weight regain occurred. The median procedure time was 68.0 minutes.
Limitations:
Small sample, single-institution experience.
Conclusion:
The internal EDGE procedure may offer a cost-effective, minimally invasive option for a common problem in a growing patient demographic. Further refinement of the technique is required to minimize adverse events. (
Clinical Trial Registration Number:
NCT01522573.).
