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Depression and anxiety in chronic rhinosinusitis
Mohamed O Tomoum1,2, Cristine Klattcromwell1, Anthony DelSignore1
1University of North Carolina at Chapel Hill, Otolaryngology/Head and Neck Surgery, Chapel Hill, NC.
International Forum of Allergy & Rhinology
|May 9, 2015
Summary
Depression and anxiety significantly impact quality of life in chronic rhinosinusitis (CRS) patients. Patient-reported outcomes, like the Rhinosinusitis Disability Index (RSDI), correlate strongly with anxiety and depression scores (HADS), not endoscopic findings.
Area of Science:
- Otolaryngology
- Psychiatry
- Quality of Life Research
Background:
- Chronic rhinosinusitis (CRS) is associated with adverse quality of life.
- Depression and anxiety are suspected contributors to reduced quality of life in CRS patients.
Purpose of the Study:
- To assess the prevalence of anxiety and depression in CRS patients.
- To evaluate the impact of anxiety and depression on quality of life in CRS.
- To analyze correlations between disease-specific (RSDI), general (HADS), and endoscopic (Lund-Kennedy) scores.
Main Methods:
- Prospective evaluation of 124 CRS patients in an outpatient setting.
- Utilized Rhinosinusitis Disability Index (RSDI) and Hospital Anxiety and Depression Score (HADS) questionnaires.
- Included Lund-Kennedy nasal endoscopic scoring for objective assessment.
Main Results:
- Moderate to very strong correlations found between RSDI and HADS scores (total and subscales).
- Poor correlation observed between RSDI/HADS scores and Lund-Kennedy endoscopic scores.
- CRS patients with higher HADS scores (indicating anxiety/depression) reported worse RSDI scores.
Conclusions:
- Anxiety and depression are prevalent in patients with chronic rhinosinusitis.
- Patient-reported quality of life (RSDI) is strongly linked to mental health status (HADS), not endoscopic severity.
- Mental health assessment is crucial for managing quality of life in CRS patients.
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