Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

844
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
844
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.3K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

671
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
671
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

51.0K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
51.0K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

17.5K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
17.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prolonged mpox infection and fatal outcome in an HIV patient treated with tecovirimat.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens.

Frontiers in immunology·2026
Same author

Genome-wide association study of idiopathic pulmonary fibrosis susceptibility using clinically curated European ancestry datasets.

The European respiratory journal·2026
Same author

Association Between Maternal Gestational Diabetes, Cord Blood DNA Methylation, and Offspring Neurodevelopment.

International journal of molecular sciences·2026
Same author

Cross-ancestry evaluation of idiopathic pulmonary fibrosis genetic risk variants.

medRxiv : the preprint server for health sciences·2026
Same author

Multi-Ancestry Epigenome-Wide Meta-Analysis Identifies Novel Bulk and Cell-Type-Specific Epigenetic Markers of Asthma with Severe Exacerbations.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Apr 12, 2026

Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons
10:24

Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons

Published on: August 29, 2014

84.9K

IonGAP: integrative bacterial genome analysis for Ion Torrent sequence data.

Adrian Baez-Ortega1, Fabian Lorenzo-Diaz2, Mariano Hernandez3

  • 1Information Technology Department, Instituto Tecnológico y de Energías Renovables (ITER), Santa Cruz de Tenerife, Spain.

Bioinformatics (Oxford, England)
|May 9, 2015
PubMed
Summary

We present IonGAP, a new bioinformatics platform for analyzing bacterial genomes from Ion Torrent sequencing data. This tool simplifies complex genomic analyses for applications in healthcare and industry.

More Related Videos

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

7.4K

Related Experiment Videos

Last Updated: Apr 12, 2026

Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons
10:24

Next-generation Sequencing of 16S Ribosomal RNA Gene Amplicons

Published on: August 29, 2014

84.9K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

7.4K

Area of Science:

  • Bioinformatics
  • Genomics
  • Microbiology

Background:

  • Whole bacterial genome analysis is crucial for public health and industry.
  • Ion Torrent sequencing offers low-cost data generation.
  • Existing platforms may lack comprehensive analysis or ease of use.

Purpose of the Study:

  • To introduce IonGAP, a web-based platform for analyzing bacterial genomes.
  • To provide a user-friendly tool for comparative genomics, annotation, and classification.
  • To facilitate low-cost bacterial genome analysis for practical applications.

Main Methods:

  • IonGAP is a web platform utilizing FASTQ, BAM, and SRA file formats.
  • It integrates assembly, comparative genomics, annotation, and classification routines.
  • The platform is hosted on the ITER's Teide-HPC supercomputer.

Main Results:

  • Benchmarking demonstrated IonGAP as a fast, powerful, and user-friendly bioinformatics tool.
  • The platform supports comprehensive analysis of whole bacterial genomes.
  • IonGAP is publicly available for non-commercial use.

Conclusions:

  • IonGAP enables efficient and accessible bacterial genome analysis.
  • The platform can translate genomic insights into actionable strategies for prevention and control.
  • IonGAP supports applications in healthcare, agroalimentary, and pharmaceutical sectors.