Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound.

Bioorganic & medicinal chemistry·2024

Same author

Population dynamics of a long-term selection experiment in White Plymouth Rock chickens selected for low or high body weight.

Poultry science·2023

Same author

Central nervous system manifestations of systemic haematological malignancies and key differentials.

Clinical radiology·2022

Same author

Arachnoid Membranes: Crawling Back into Radiologic Consciousness.

AJNR. American journal of neuroradiology·2021

Same author

Evaluation of the Impact of Magnetic Resonance Imaging with Susceptibility-weighted Imaging for Screening and Surveillance of Radiation-induced Cavernomas in Long-term Survivors of Malignancy.

Clinical oncology (Royal College of Radiologists (Great Britain))·2021

Same author

The imaging of immunotherapy-related hypophysitis and other pituitary lesions in oncology patients.

Clinical radiology·2021

Same journal

Diagnostic accuracy of flat panel computed tomography for acute stroke: a systematic review and meta-analysis of diagnostic test accuracy studies.

Clinical radiology·2026

Same journal

Nuclear medicine techniques in gynaecological malignancy: a review of best practice.

Clinical radiology·2026

Same journal

Deep learning reconstruction dual-energy computed tomography for gastrointestinal system tumors: low-kiloelectron volt imaging vs routine imaging.

Clinical radiology·2026

Same journal

Deep learning-based reconstruction for 5.0T magnetic resonance imaging (MRI) in nasopharyngeal carcinoma: comparison of image quality and diagnostic efficacy.

Clinical radiology·2026

Same journal

Papillary muscle fibrosis on cardiac magnetic resonance imaging: a pictorial review of causes, diagnostic challenges and practical pearls.

Clinical radiology·2026

Same journal

Deep learning-based automated assessment of pulmonary artery indices and surgical approach triage for tetralogy of Fallot from multicenter cardiac computed tomography (CT).

Clinical radiology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 12, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Intracranial involvement by multiple myeloma.

A Lasocki¹, S Gangatharan², F Gaillard³

¹Department of Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Diagnostic Imaging, Monash Health, Clayton, Victoria, Australia.

Clinical Radiology

|May 10, 2015

Summary

This summary is machine-generated.

Intracranial involvement in multiple myeloma is rare, arising from direct spread or blood dissemination. This review highlights the diverse neuroimaging findings, particularly on MRI, for this uncommon complication.

More Related Videos

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

Related Experiment Videos

Last Updated: Apr 12, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

Area of Science:

Neurology
Oncology
Radiology

Background:

Multiple myeloma is a plasma cell malignancy.
Intracranial involvement is an infrequent but serious complication.
This can manifest as dural, leptomeningeal, or parenchymal disease.

Purpose of the Study:

To review and illustrate the neuroimaging features of intracranial multiple myeloma.
To focus on magnetic resonance imaging (MRI) findings.
To aid in the diagnosis of this rare entity.

Main Methods:

Literature review of cases with intracranial multiple myeloma.
Analysis of neuroimaging findings, primarily MRI.
Correlation of imaging with pathological findings where available.

Main Results:

Intracranial involvement can occur via direct extension or hematogenous spread.
Neuroimaging findings are often non-specific.
Various patterns of dural, leptomeningeal, and parenchymal disease are observed on MRI.

Conclusions:

Intracranial involvement in multiple myeloma requires high suspicion.
MRI is crucial for detecting and characterizing these lesions.
Radiologists and clinicians should be aware of the diverse imaging spectrum.