Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

25.0K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
25.0K
Gustation01:43

Gustation

53.7K
Gustation is a chemical sense that, along with olfaction (smell), contributes to our perception of taste. It starts with the activation of receptors by chemical compounds (tastants) dissolved in the saliva. The saliva and filiform papillae on the tongue distribute the tastants and increase their exposure to the taste receptors.
53.7K
Taste Buds and Receptors01:20

Taste Buds and Receptors

6.1K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
6.1K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

1.4K
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
1.4K
Regulation of Food Intake01:30

Regulation of Food Intake

3.2K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
3.2K
Neural Regulation01:37

Neural Regulation

45.1K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
45.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Musculoskeletal Pain With Foot Type, Plantar Pressure, Physical Activity, Psychosocial Factors, and Daily Living Habits Among Adolescents.

Clinical medicine insights. Arthritis and musculoskeletal disorders·2026
Same author

Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes.

Gut microbes·2025
Same author

An enhanced recovery after surgery for the Nuss procedure for pectus excavatum in pediatric patients in Shanghai.

Pediatric surgery international·2025
Same author

Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice.

GeroScience·2025
Same author

Response inhibition and morphological awareness in children with attention deficit hyperactivity disorder: evidence from behavior and ERPs.

PeerJ·2025
Same author

Managing Glucose Homeostasis Through the Gut Microbiome.

Annual review of physiology·2025

Related Experiment Video

Updated: Apr 12, 2026

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
07:29

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation

Published on: December 29, 2023

1.2K

Does nutrient sensing determine how we "see" food?

Sophie C Hamr1, Beini Wang, Timothy D Swartz

  • 1Department of Physiology, University of Toronto, Toronto, M5S 1A8, Canada, sophie.hamr@mail.utoronto.ca.

Current Diabetes Reports
|May 10, 2015
PubMed
Summary
This summary is machine-generated.

Nutrient sensing in the gut and brain is crucial for energy balance and glucose control. Disruptions in these nutrient-sensing pathways can lead to obesity and type 2 diabetes.

More Related Videos

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
06:45

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

7.2K
Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging
07:25

Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging

Published on: April 29, 2016

9.1K

Related Experiment Videos

Last Updated: Apr 12, 2026

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
07:29

Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation

Published on: December 29, 2023

1.2K
A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
06:45

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

7.2K
Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging
07:25

Measuring Physiological Responses of Drosophila Sensory Neurons to Lipid Pheromones Using Live Calcium Imaging

Published on: April 29, 2016

9.1K

Area of Science:

  • Physiology
  • Metabolism
  • Neuroendocrinology

Background:

  • Energy homeostasis relies on sensing incoming and circulating nutrients.
  • Nutrient-sensing mechanisms in the gastrointestinal tract and brain regulate energy intake and glucose levels.
  • The intestinal wall differentiates nutrients via mucosal sensory machinery, signaling via gut peptides to maintain energy balance.

Purpose of the Study:

  • To review the evidence for nutrient sensing in energy balance regulation.
  • To explore the roles of intestinal and brain nutrient sensing.
  • To discuss the link between disrupted nutrient sensing and metabolic diseases like obesity and type 2 diabetes.

Main Methods:

  • Literature review of existing research.
  • Analysis of studies on nutrient-sensing pathways.
  • Synthesis of findings on gut-brain nutrient signaling.

Main Results:

  • Intestinal sensing mechanisms differentiate nutrients and influence energy intake.
  • Brain regions like the hypothalamus and hindbrain detect circulating nutrients.
  • Nutrient sensing in the intestine can stimulate food intake and preferences.

Conclusions:

  • Nutrient sensing in the intestine and brain is vital for maintaining energy balance.
  • Dysregulation of these nutrient-sensing pathways is implicated in obesity and type 2 diabetes.
  • Further research into these mechanisms could offer therapeutic targets for metabolic disorders.