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Generalised cognitive motor interference in multiple sclerosis.

Y C Learmonth1, L A Pilutti1, R W Motl1

  • 1Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 233 Freer Hall, Urbana, IL 61820, USA.

Gait & Posture
|May 11, 2015
PubMed
Summary

Cognitive motor interference impacts both upper and lower extremities in individuals with multiple sclerosis (MS) and healthy controls. This interference is comparable across different MS disability levels, affecting walking and fine motor skills.

Keywords:
Cognitive motor interferenceDual taskLower extremityMultiple sclerosisUpper extremity

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Area of Science:

  • Neuroscience
  • Motor Control
  • Rehabilitation Science

Background:

  • Cognitive motor interference (CMI) has been studied in lower extremity function for multiple sclerosis (MS).
  • However, CMI in upper extremity function for MS has not been previously investigated.
  • Understanding CMI in both upper and lower extremities is crucial for comprehensive rehabilitation strategies in MS.

Purpose of the Study:

  • To investigate cognitive motor interference (CMI) in both lower and upper extremity motor tasks.
  • To compare CMI between individuals with MS and those without MS (controls).
  • To examine the relationship between CMI and disability levels in individuals with MS.

Main Methods:

  • Eighty-two participants (with and without MS) performed walking (gait velocity) and the nine-hole peg test (NHPT) under single-task and dual-task conditions.
  • Gait velocity was measured using a GAITRite electronic walkway.
  • Data were analyzed using mixed-factor ANOVA and Pearson correlations.

Main Results:

  • Significant Task main effects were observed for both gait velocity and NHPT performance in both MS and control groups, indicating substantial CMI.
  • These effects were comparable between individuals with and without MS.
  • CMI for walking and the NHPT were significantly correlated across all participants, including those with varying MS disability levels.

Conclusions:

  • Cognitive motor interference affects both upper and lower extremities in individuals with MS.
  • The degree of CMI is similar between individuals with and without MS.
  • CMI is consistent across different levels of MS-related disability, suggesting a unified impact on motor function.