Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

1.5K
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
1.5K
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

790
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
790
Borderline Personality Disorder01:25

Borderline Personality Disorder

1.0K
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
1.0K
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

872
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
872
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

1.2K
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.2K
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

1.2K
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acceptability and safety of two sequential doses of psilocybin in bipolar II depression: protocol for an open-label single-arm feasibility study.

BMJ open·2026
Same author

Challenges with clinical trial participants in studies with classical psychedelics: A position statement from the National Network of Depression Centers' task group on psychedelics and related compounds.

Journal of psychopharmacology (Oxford, England)·2026
Same author

Connecting, Serving, and Adapting: Perspectives on the Transition to Adulthood from Latino Young Adults with ASD, Parents, and Providers.

Journal of developmental and physical disabilities·2026
Same author

Contemplating versus having used psychedelics in bipolar disorder - What makes the difference?

Journal of affective disorders·2025
Same author

Corrigendum to "The role of the psychedelic experience in psilocybin treatment for treatment-resistant depression" [Journal of Affective Disorders, Volume 372 (2025), Pages 523-532].

Journal of affective disorders·2025
Same author

Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus.

Nature communications·2025

Related Experiment Video

Updated: Apr 12, 2026

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
09:12

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Published on: March 17, 2019

10.5K

Impulsivity: present during euthymia in bipolar disorder? - a systematic review.

Antonia L Newman1, Thomas D Meyer2

  • 1Northumberland, Tyne and Wear NHS Foundation Trust, St Nicholas Hospital, Gosforth, Newcastle upon Tyne, NE3 3XT UK.

International Journal of Bipolar Disorders
|May 12, 2015
PubMed
Summary

Euthymic patients with bipolar disorder (BD) report higher impulsivity on self-ratings, but behavioral measures show limited evidence. Further research is needed to confirm impulsivity as a vulnerability marker for BD.

Keywords:
Bipolar disorderDelay of gratificationEuthymiaImpulsivityResponse inhibitionSelf-report

More Related Videos

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.7K
A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

22.6K

Related Experiment Videos

Last Updated: Apr 12, 2026

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
09:12

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Published on: March 17, 2019

10.5K
Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

1.7K
A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

22.6K

Area of Science:

  • Psychiatry
  • Neuroscience
  • Psychology

Background:

  • Impulsivity is a key feature of bipolar disorder (BD).
  • Understanding impulsivity in stable mood states may reveal vulnerability markers for BD.

Purpose of the Study:

  • To systematically review evidence on increased impulsivity in euthymic bipolar disorder patients.
  • To explore different facets of impulsivity as potential vulnerability markers for BD.

Main Methods:

  • Systematic review of 23 studies.
  • Analysis of self-report trait impulsivity measures.
  • Analysis of behavioral paradigms: response inhibition and delay of gratification.

Main Results:

  • Most self-report studies found higher impulsivity in euthymic BD patients compared to controls.
  • Limited evidence for increased impulsivity on behavioral measures, particularly response inhibition.
  • Few studies on delay of gratification, with strongest studies showing no group differences.

Conclusions:

  • Euthymic BD patients report increased impulsivity via self-ratings.
  • Behavioral evidence for impulsivity in BD is limited, possibly related to illness severity.
  • More research on delay of gratification and at-risk individuals is needed to establish impulsivity as a vulnerability marker.