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Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Perception of dyspnea in children with asthma
Konstantinos Douros1, Barbara Boutopoulou, Marios Papadopoulos
13rd Dpt of Pediatrics, Attikon Hospital, 1 Rimini Str, Chaidari 12464, Greece, costasdouros@gmail.com.
Insights
Dyspnea, or breathlessness, is a complex symptom with poorly understood mechanisms. Accurate perception of dyspnea is crucial for timely asthma diagnosis and treatment.
Area of Science:
- Respiratory Medicine
- Symptom Perception
- Psycho-physiology
Background:
- Dyspnea (breathlessness) is a subjective symptom with complex, multifactorial causes and largely undefined psycho-physiologic mechanisms.
- At least three distinct qualities of dyspnea suggest different underlying respiratory stresses and mechanisms.
- Current methods for measuring dyspnea lack standardization, particularly in pediatric populations.
Purpose of the Study:
- To explore the complex nature of dyspnea perception.
- To highlight the challenges in standardizing dyspnea measurement, especially in children.
- To emphasize the clinical implications of altered dyspnea perception in managing respiratory conditions like asthma.
Main Methods:
- Review of existing literature on dyspnea.
- Analysis of the relationship between subjective dyspnea and objective lung function measures.
- Discussion of measurement challenges and standardization issues.
Main Results:
- Significant discrepancies exist between patients' subjective rating of dyspnea severity and objective lung function tests.
- The same level of bronchoconstriction can elicit varied dyspnea perceptions among individuals.
- Lack of standardized measurement tools hinders accurate assessment, particularly in children.
Conclusions:
- Altered perception of dyspnea can lead to delayed diagnosis and undertreatment of respiratory diseases such as asthma.
- Further research is needed to standardize dyspnea measurement and elucidate its underlying mechanisms.
- Improved understanding and assessment of dyspnea are vital for effective patient management.
Abstract:
The subjective experience of discomfort in breathing, termed dyspnea (or breathlessness), is a symptom with multifactorial causes of highly complex and largely undefined psycho-physiologic mechanism(s). There are at least three discrete qualities of dyspnea likely corresponding to different types of respiratory stress and separate underlying mechanisms. Perception of dyspnea can be measured by diverse means; however, none of these scales has been standardized in children. In general, the same degree of bronchoconstriction causes various levels of perception of dyspnea in different patients. There are large discrepancies among patients in subjective rating of the severity of dyspnea and objective measurement of lung function. Since reporting symptoms is an integral part of therapeutic management of asthma, poor perception of dyspnea may lead to delayed diagnosis and undertreatment of the disease.
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