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Published on: March 1, 2024
Epidemiology and Comorbidity in Children with Psoriasis and Atopic Eczema
Matthias Augustin1, Marc A Radtke, Gerd Glaeske
1Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany.
Insights
Juvenile psoriasis and atopic eczema in children present distinct comorbidity profiles. Early detection and adequate treatment of these conditions are crucial for better health outcomes.
Area of Science:
- Pediatric Dermatology
- Public Health
- Epidemiology
Background:
- Juvenile psoriasis is linked to a higher prevalence of comorbidities.
- Understanding these comorbidities is essential for managing childhood skin conditions.
Purpose of the Study:
- To analyze and characterize comorbidity profiles in children diagnosed with psoriasis and atopic eczema.
- To compare comorbidity patterns between these two pediatric dermatological conditions.
Main Methods:
- Utilized a German statutory health insurance database for prevalence data.
- Analyzed ICD-10 codes L40 (psoriasis) and L20 (atopic eczema) for children up to 18 years old in 2009.
- Included data from 1.64 million individuals, with 293,181 children.
Main Results:
- Identified 1,313 children (0.45%) with psoriasis and 30,354 children (10.35%) with atopic eczema.
- Children with psoriasis showed higher rates of obesity, hyperlipidaemia, arterial hypertension, and diabetes compared to controls and those with atopic eczema.
- Distinct comorbidity patterns were observed between pediatric psoriasis and atopic eczema cohorts.
Conclusions:
- Children with psoriasis and atopic eczema exhibit unique comorbidity patterns.
- Early identification and appropriate management of these comorbidities are recommended.
- This study highlights the importance of a comprehensive approach to managing pediatric dermatological conditions.
Background:
First studies have shown that juvenile psoriasis is associated with an increased prevalence of comorbidity.
Objectives:
We carried out a data analysis to characterise the profiles of comorbidity in children with psoriasis and atopic eczema.
Methods:
Prevalence data were derived from the database of a German statutory health insurance company according to ICD-10 codes L40 (psoriasis) and L20 (atopic eczema) of children up to 18 years insured in 2009.
Results:
Data sets included 1.64 million persons and 293,181 children. 1,313 children = 0.45% (0.42-0.47) had a diagnosis of psoriasis and 30,354 = 10.35% (10.24-10.47) had a diagnosis of atopic eczema. Obesity, hyperlipidaemia, arterial hypertension and diabetes were more often diagnosed in children with psoriasis in comparison to all children without psoriasis and to those with atopic eczema.
Conclusion:
Children with psoriasis and atopic eczema show different and specific patterns of comorbidity which should be detected early and treated adequately.
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