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Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11
Y Edwards1, L West, V Van Heyningen
1MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London.
Annals of Human Genetics
|July 1, 1989
Abstract:
A cDNA clone complementary to the mRNA encoding the sperm-specific lactate dehydrogenase, LDHC, has been used to map the LDHC locus to the short arm of human chromosome 11. In situ hybridization data and analysis of mouse/human somatic cell hybrids carrying deletions of human chromosome 11 suggest that the gene is localized at p15.3-p15.5 close to the LDHA gene.