Related Experiment Video
Updated: Apr 12, 2026

Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
Published on: January 7, 2015
Autologous fat grafting in facial volumetric restoration
Pasquale Piombino, Piombino Pasquale1, Gaetano Marenzi
1*Ear Nose Throat Department, Second University of Naples, Naples, Italy †Oral Surgery Division ‡Division of Maxillofacial Surgery §Division of MaxilloFacial Surgery ||Oral Surgery Division, Department of Neurosciences, Reproductive and Odontostomatologic Sciences, University of Naples "Federico II", Naples, Italy.
Abstract:
The authors reported their surgical experience about structural fat grafting in the management of facial volumetric deficit. The purpose of this study was to assess the real indications, cosmetic results, complications, and global patient satisfaction of the Coleman technique in redefining facial contours in congenital and postoperative deformities. A retrospective analysis of 32 patients grafted according to Coleman's technique was performed, and the long-term outcomes and patient satisfaction were evaluated. The mean postoperative clinical follow-up was 14 months. The morphological changes were analyzed by comparing the photographic presurgical facial contour and the postoperative correction of soft tissue defects. All consecutive cases reported showed a progressive fat resorption for 3 months after surgery and its stable integration only after this period. Best results were performed in the treatment of genetically determined syndromes, such as the Franceschetti and Romberg syndromes. The authors suggest this surgical technique also for the treatment of unaesthetic cutaneous abscess cavity after incision and drainage. Unsatisfactory outcomes were obtained in the treatment of the posttraumatic facial scar, which needed more surgical procedures.

