Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antifungal Agents01:15

Antifungal Agents

89
Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
89
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants

2.3K

Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
2.3K
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

2.1K
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
2.1K
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:22

Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

2.5K
Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
The direct-acting...
2.5K
Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

30.1K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
30.1K
Adrenergic Agonists: Indirect-Acting Agents01:25

Adrenergic Agonists: Indirect-Acting Agents

3.1K
Indirect-acting adrenergic agonists potentiate the effects of endogenous catecholamines through different mechanisms without directly binding to adrenoceptors.
One mechanism involves depleting stored catecholamines by displacing them from synaptic vesicles. These agents, known as "displacers," are transported into vesicles at the expense of noradrenaline. Examples include amphetamine and tyramine, which lack a catechol moiety, resulting in prolonged action, improved oral...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel dual-action compound from the Western Ghats tree <i>Poeciloneuron indicum</i> targets acetylcholinesterase and neprilysin in Alzheimer's disease.

Natural product research·2026
Same author

Chondroprotective effects of madecassoside incorporated alginate di-aldehyde gelatin hydrogel on IL-1 β induced in vitro osteoarthritic model.

International journal of biological macromolecules·2025
Same author

Protective activity of bacopaside I encapsulated polymeric nanoparticles against kainic acid-induced excitotoxicity.

Tissue barriers·2025
Same author

Plants used in Ayurveda for Jwara or fever: A review of their antiviral studies.

Journal of Ayurveda and integrative medicine·2025
Same author

Protection by Nano-Encapsulated Bacoside A and Bacopaside I in Seizure Alleviation and Improvement in Sleep- In Vitro and In Vivo Evidences.

Molecular neurobiology·2023
Same author

Ethyl palmitate, an anti-chikungunya virus principle from Sauropus androgynus, a medicinal plant used to alleviate fever in ethnomedicine.

Journal of ethnopharmacology·2023
Same journal

Five undescribed compounds isolated from Gerbera delavayi with their anti-inflammatory activity.

Phytochemistry·2026
Same journal

Ingenane diterpenoids with anti-inflammatory activity from the whole plants of Euphorbia peplus.

Phytochemistry·2026
Same journal

Discovery of cytotoxic 1,4-benzodioxane oxyneolignan analogues from Glechoma longituba.

Phytochemistry·2026
Same journal

Cinnamolides A-G, seven previously undescribed phytoconstituents from the peels of Cinnamomum chago and their anti-inflammatory activity.

Phytochemistry·2026
Same journal

Antiviral amide derivatives from Uvaria siamensis.

Phytochemistry·2026
Same journal

COX-2 inhibitors from Laportea bulbifera: Structure-activity relationship, kinetic investigation, and molecular docking.

Phytochemistry·2026
See all related articles

Related Experiment Video

Updated: Apr 12, 2026

Isolation and Purification of Fungal &#946;-Glucan as an Immunotherapy Strategy for Glioblastoma
10:02

Isolation and Purification of Fungal β-Glucan as an Immunotherapy Strategy for Glioblastoma

Published on: June 2, 2023

2.7K

Secondary metabolites from Ganoderma.

Sabulal Baby1, Anil John Johnson1, Balaji Govindan1

  • 1Phytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram 695 562, Kerala, India.

Phytochemistry
|May 16, 2015
PubMed
Summary
This summary is machine-generated.

This review details 431 secondary metabolites from medicinal Ganoderma mushrooms, highlighting their diverse chemical structures and biological significance. Further research promises new discoveries in Ganoderma

Keywords:
Biological activitiesGanoderic acidsGanodermaGanodermataceaeLanostane type triterpenoidsLucidenic acidsMeroterpenoidsSteroidsVolatiles

More Related Videos

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

3.1K

Related Experiment Videos

Last Updated: Apr 12, 2026

Isolation and Purification of Fungal &#946;-Glucan as an Immunotherapy Strategy for Glioblastoma
10:02

Isolation and Purification of Fungal β-Glucan as an Immunotherapy Strategy for Glioblastoma

Published on: June 2, 2023

2.7K
Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

3.1K

Area of Science:

  • Mycology
  • Natural Product Chemistry
  • Pharmacognosy

Background:

  • Ganoderma mushrooms are recognized for their medicinal properties.
  • Phytochemical investigation of Ganoderma species has a long history.
  • Secondary metabolites from Ganoderma exhibit diverse biological activities.

Purpose of the Study:

  • To review secondary metabolites isolated from Ganoderma species.
  • To discuss the biological significance of these compounds.
  • To identify gaps and future directions in Ganoderma phytochemical research.

Main Methods:

  • Comprehensive literature review of phytochemical studies on Ganoderma.
  • Analysis of reported secondary metabolites and their chemical classes.
  • Compilation of biological activities associated with isolated compounds.

Main Results:

  • Over 431 secondary metabolites have been identified across various Ganoderma species.
  • Major compound classes include lanostanes (ganoderic and lucidenic acids), triterpenes, meroterpenoids, and steroids.
  • Ganoderma lucidum is the most extensively studied species, with numerous other species also investigated.

Conclusions:

  • Ganoderma mushrooms are a rich source of diverse secondary metabolites.
  • Continued phytochemical exploration of Ganoderma species is crucial for discovering novel bioactive compounds.
  • Understanding these metabolites can lead to new therapeutic applications.