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Boston type 1 keratoprosthesis for failed keratoplasty
Jonathan L Hager1,2, David L Phillips1,2, Kenneth M Goins1,2
1Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA, 52242-1091, USA.
International Ophthalmology
|May 16, 2015
Summary
The Boston type 1 keratoprosthesis (Kpro-1) shows excellent retention and visual improvement in eyes with failed corneal transplants. This artificial cornea offers a viable solution for complex cases, despite some serious complications.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Prosthetic Devices
Background:
- Corneal transplantation is a common procedure for vision restoration.
- Failed keratoplasty presents significant challenges for visual rehabilitation.
- Artificial cornea devices offer an alternative for eyes unsuitable for repeat transplantation.
Purpose of the Study:
- To evaluate the outcomes of the Boston type 1 keratoprosthesis (Kpro-1).
- To assess Kpro-1 efficacy in eyes with prior failed corneal grafts.
- To analyze visual outcomes, prosthesis retention, and complications.
Main Methods:
- Retrospective review of patients receiving Kpro-1 between 2008 and 2013.
- Inclusion criteria: failed keratoplasty for corneal edema, trauma, or keratoconus.
- Outcome measures: visual acuity, prosthesis survival, and complications.
Main Results:
- 24 eyes met inclusion criteria; mean follow-up 28.9 months.
- Median best corrected visual acuity (BCVA) improved to 20/125; 58.3% achieved ≥20/200.
- Prosthesis retention was high (91.7%); 33.3% experienced serious complications.
Conclusions:
- Boston Kpro-1 demonstrates excellent prosthesis retention rates.
- Satisfactory visual improvement is achievable in eyes with failed keratoplasty.
- Careful patient selection and management are crucial due to potential complications.

