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Mechanical failures of the pneumatic Utah-100 and Jarvik total artificial hearts. A comparative study
P A Dew1, G M Pantalos, J W Holfert
1Artificial Heart Research Laboratory, University of Utah, Salt Lake City 84103-1414.
Abstract:
Jarvik-5 and Jarvik-7 total artificial hearts (TAHs) and Utah-100 TAHs were fabricated and implanted in calves and sheep. In the Jarvik series, 30.7% had mechanical failures (16.1% catastrophic). In the Utah-100 TAH series, 11.1% had mechanical failures (3.7% catastrophic). Failures were classified as: 1) diaphragm failures; 2) valve-holding ring failures; 3) air-leak failures; and 4) prosthetic valve failures. Marked reduction in mechanical failure for the Utah-100 TAH is attributed to progressive component redesign, material selection, and more stringent quality control criteria.