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Chiral resolution capabilities of DNA oligonucleotides

Luma Tohala1, Farid Oukacine1, Corinne Ravelet1

  • 1Université Grenoble Alpes, DPM UMR 5063, F-38041 Grenoble, CNRS, DPM UMR 5063, F-38041 Grenoble, France.

Analytical Chemistry
|May 16, 2015
PubMed
Summary

DNA oligonucleotides (ONs) effectively separate chiral molecules. Researchers screened ten diverse ON sequences, demonstrating their capability to resolve approximately 20 different racemates, including drugs and amino acids, in capillary electrophoresis. This highlights ONs as versatile chiral separation tools.

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