Related Experiment Video
Updated: Apr 12, 2026

11:21
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
12.1K
INTRASURGICAL MICROSCOPE-INTEGRATED SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY-ASSISTED MEMBRANE PEELING
Christiane I Falkner-Radler1, Carl Glittenberg, Max Gabriel
1Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery, Department of Ophthalmology, Rudolf Foundation Clinic, Teaching Hospital of the Medical University, Vienna, Austria.
Retina (Philadelphia, Pa.)
|May 16, 2015
Summary
Intraoperative spectral domain optical coherence tomography (iSD-OCT) aids macular surgery by visualizing membranes. It proved comparable to retinal dyes for confirming successful membrane peeling, though staining offered better visualization of flat membranes.
Area of Science:
- Ophthalmology
- Surgical Technology
- Medical Imaging
Background:
- Macular surgery, including epiretinal membrane removal and treatment of macular holes, requires precise visualization.
- Traditional methods like retinal staining can have limitations and potential toxicity.
Purpose of the Study:
- To evaluate the efficacy of microscope-integrated intrasurgical spectral domain optical coherence tomography (iSD-OCT) during macular surgery.
- To compare iSD-OCT with conventional retinal staining for assessing surgical outcomes.
Main Methods:
- A prospective monocenter study involving 51 patients undergoing macular surgery.
- Intrasurgical spectral domain optical coherence tomography (iSD-OCT) scans were performed using a microscope-integrated system before, during, and after membrane peeling.
- Results were compared with retinal staining outcomes.
Main Results:
- iSD-OCT enabled membrane peeling without retinal dyes in 40% of cases.
- No residual membranes were detected by iSD-OCT or staining in 94.3% of patients.
- iSD-OCT facilitated intraocular tamponade decisions in vitreomacular traction cases.
Conclusions:
- Intrasurgical spectral domain optical coherence tomography (iSD-OCT) is a viable tool for confirming successful membrane peeling in macular surgery, comparable to retinal dyes.
- While iSD-OCT is effective, retinal staining provided superior visualization of flat membranes.

