Related Experiment Video For Head and neck cancer
Updated: Apr 12, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Molecular biology and immunology of head and neck cancer
Theresa Guo1, Joseph A Califano1
1Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins Medical Institutions, 1550 Orleans St, Baltimore, MD 21231, USA.
Abstract:
In recent years, our knowledge and understanding of head and neck squamous cell carcinoma (HNSCC) has expanded dramatically. New high-throughput sequencing technologies have accelerated these discoveries since the first reports of whole-exome sequencing of HNSCC tumors in 2011. In addition, the discovery of human papillomavirus in relationship with oropharyngeal squamous cell carcinoma has shifted our molecular understanding of the disease. New investigation into the role of immune evasion in HNSCC has also led to potential novel therapies based on immune-specific systemic therapies.
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