Related Experiment Video
Updated: Apr 12, 2026

High-throughput Siderophore Screening from Environmental Samples: Plant Tissues, Bulk Soils, and Rhizosphere Soils
Published on: February 9, 2019
Characterization of microbial siderophores by mass spectrometry
Tomáš Pluháček1,2, Karel Lemr1,2, Dipankar Ghosh3
1Department of Analytical Chemistry, Faculty of Science, Regional Centre of Advanced Technologies and Materials, Palacky University, 17. listopadu 12, 771 46, Olomouc, Czech Republic.
Abstract:
Siderophores play important roles in microbial iron piracy, and are applied as infectious disease biomarkers and novel pharmaceutical drugs. Inductively coupled plasma and molecular mass spectrometry (ICP-MS) combined with high resolution separations allow characterization of siderophores in complex samples taking advantages of mass defect data filtering, tandem mass spectrometry, and iron-containing compound quantitation. The enrichment approaches used in siderophore analysis and current ICP-MS technologies are reviewed. The recent tools for fast dereplication of secondary metabolites and their databases are reported. This review on siderophores is concluded with their recent medical, biochemical, geochemical, and agricultural applications in mass spectrometry context.
Related Concept Videos
MALDI-TOF Mass Spectrometry
Mass Spectrometry: Overview
High-Resolution Mass Spectrometry (HRMS)
Mass Spectrometers
Mass Spectrometry: Isotope Effect
Mass Spectrum: Interpretation

