When is a two-stent technique needed and which technique should then be used for bifurcation coronary lesions?

Although the guidelines recommend the provisional one-stent technique as a default technique for bifurcation coronary lesions, there are cases of bifurcations with large side branches (SB), difficult access and with ostial and diffuse disease extending more than 5 mm into the SB, where a two-stent strategy might be the best treatment option. Due to the inherent advantages and disadvantages of each two-stent technique, an appropriate technique should be selected according to each patient's clinical condition, bifurcation morphology and the operator's experience. Good long-term prognosis is most likely ensured by successful performance of each procedural step during the initial stenting.