Infective Endocarditis Presenting as Acute Renal Failure and Unusual Complications

Luciano Pereira1, Ana Machado, Jorge Oliveira

  • 1����Nephrology Research and Development Unit, Faculty of Medicine, University of Porto, 2.Nephrology Department, São João Hospital Center, Portugal.

Insights

Infective endocarditis, a heart valve infection, can present unusually with kidney failure and rare complications like pseudoaneurysms and splenic abscess. Prompt antibiotic treatment led to clinical improvement, though renal function did not recover.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Nephrology

Background:

  • Infective endocarditis (IE) poses diagnostic challenges, with renal failure being an uncommon presentation.
  • Rare complications of IE include pseudoaneurysms and splenic abscesses.

Observation:

  • An 80-year-old male presented with anorexia, malaise, edema, and acute renal failure.
  • Blood cultures identified Enterococcus faecalis; treatment included ampicillin and gentamicin.
  • Transesophageal echocardiography revealed pseudoaneurysms in the mitral-aortic intervalvular fibrosa and aortic root.
  • Abdominal CT scan demonstrated a splenic abscess.

Findings:

  • The patient received 6 weeks of antibiotics, showing clinical improvement and splenic abscess regression.
  • Despite treatment, renal function did not recover, necessitating ongoing hemodialysis.

Implications:

  • This case highlights unusual IE presentations and complications, emphasizing the importance of comprehensive diagnosis.
  • Successful antibiotic management of IE-related pseudoaneurysms and splenic abscesses is demonstrated.
  • The case underscores the potential for irreversible renal damage in complicated IE.

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