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Infective Endocarditis Presenting as Acute Renal Failure and Unusual Complications
Luciano Pereira1, Ana Machado, Jorge Oliveira
1����Nephrology Research and Development Unit, Faculty of Medicine, University of Porto, 2.Nephrology Department, São João Hospital Center, Portugal.
Abstract:
Infective endocarditis can be a diagnostic challenge. Few cases have so far reported infective endocarditis presenting as renal failure. Pseudoaneurysms of the mitral-aortic intervalvular fibrosa and splenic abscess are rare complications of infective endocarditis. We herein report a case of an 80-year-old man admitted due to anorexia, malaise, edema of the legs and renal failure. A progressive degradation of the patient's renal function was documented and hemodialysis was started. Blood cultures revealed the presence of Enterococcus faecalis, and the patient was treated with ampicillin and gentamicin. The transesophageal echocardiogram findings showed pseudoaneurysms of the mitral-aortic intervalvular fibrosa and in the aortic root wall. Due to abdominal pain, an abdominal CT scan was performed and showed a cystic lesion compatible with splenic abscess. The patient received 6 weeks of antibiotic treatment. There was progressive clinical improvement and regression of the splenic abscess, but no recovery of the renal function. This report illustrates an unusual clinical presentation of infective endocarditis with unusual complications that were successfully treated with antibiotics.
Insights
Infective endocarditis, a heart valve infection, can present unusually with kidney failure and rare complications like pseudoaneurysms and splenic abscess. Prompt antibiotic treatment led to clinical improvement, though renal function did not recover.
Area of Science:
- Cardiology
- Infectious Diseases
- Nephrology
Background:
- Infective endocarditis (IE) poses diagnostic challenges, with renal failure being an uncommon presentation.
- Rare complications of IE include pseudoaneurysms and splenic abscesses.
Observation:
- An 80-year-old male presented with anorexia, malaise, edema, and acute renal failure.
- Blood cultures identified Enterococcus faecalis; treatment included ampicillin and gentamicin.
- Transesophageal echocardiography revealed pseudoaneurysms in the mitral-aortic intervalvular fibrosa and aortic root.
- Abdominal CT scan demonstrated a splenic abscess.
Findings:
- The patient received 6 weeks of antibiotics, showing clinical improvement and splenic abscess regression.
- Despite treatment, renal function did not recover, necessitating ongoing hemodialysis.
Implications:
- This case highlights unusual IE presentations and complications, emphasizing the importance of comprehensive diagnosis.
- Successful antibiotic management of IE-related pseudoaneurysms and splenic abscesses is demonstrated.
- The case underscores the potential for irreversible renal damage in complicated IE.
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