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Updated: Apr 12, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
The Epidemiology of Methicillin-Resistant Staphylococcus aureus in Orthopaedics
1Mary Atkinson Smith, DNP, NP-C, ONP-C, Board Certified Nurse Practitioner and RNFA, Starkville Orthopedic Clinic, Starkville, Mississippi; Board Certified Nurse Practitioner, UMMC Center for TeleHealth, Jackson, Mississippi; and Assistant Professor & Assistant Program Director for Online Programs, South University College of Nursing and Public Health.
Abstract:
In the specialty of orthopaedics, methicillin-resistant Staphylococcus aureus (MRSA) is a major contributor to infections of the soft tissues, surgical sites, and joints, in addition to increasing disability, mortality, and healthcare costs. Inappropriate prescribing and misuse of antibiotics have led to bacterial resistance and the rapid emergence of MRSA. It is imperative for healthcare providers and facilities to improve quality, promote safety, and decrease costs related to MRSA infections. The healthcare profession and society as a whole play an important role in minimizing the transmission of pathogens, reducing the incidence of MRSA infections, and decreasing the development of future antibiotic resistant pathogens. This article discusses the epidemiology of MRSA and describes evidence-based guidelines pertaining to the prevention, minimization, and treatment of MRSA-related infections. Specific application to orthopaedics are discussed in the context of patient risk factors, perioperative and postoperative prophylaxis, and current trends regarding education and reporting strategies.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) poses significant risks in orthopaedics, leading to infections and increased costs. This article outlines evidence-based strategies for preventing and treating MRSA to improve patient safety and reduce antibiotic resistance.
Area of Science:
- Orthopaedics
- Infectious Diseases
- Public Health
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of orthopaedic infections, increasing morbidity, mortality, and healthcare expenses.
- Antibiotic resistance, driven by inappropriate prescribing and misuse, has led to the emergence and spread of MRSA.
- Effective strategies are crucial for healthcare providers to manage MRSA infections, enhance patient safety, and control costs.
Purpose of the Study:
- To discuss the epidemiology of MRSA in orthopaedics.
- To present evidence-based guidelines for the prevention, minimization, and treatment of MRSA infections.
- To highlight specific applications in orthopaedics, including risk factors, prophylaxis, and current trends.
Main Methods:
- Review of the epidemiology of MRSA.
- Analysis of evidence-based guidelines for MRSA management.
- Discussion of orthopaedic-specific considerations, including patient risk stratification and perioperative protocols.
Main Results:
- MRSA infections in orthopaedics contribute to substantial patient disability and healthcare costs.
- Evidence-based guidelines offer a framework for reducing MRSA incidence and improving treatment outcomes.
- Proactive measures, including appropriate prophylaxis and enhanced surveillance, are key to controlling MRSA.
Conclusions:
- Minimizing MRSA transmission and infection incidence requires a concerted effort from healthcare professionals and society.
- Implementing evidence-based guidelines is essential for improving quality, safety, and cost-effectiveness in managing MRSA infections.
- Addressing patient risk factors and optimizing perioperative care are critical components of MRSA control in orthopaedics.
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