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Progression of blood pressure and cardiovascular outcomes in hypertensive patients in a reference center
Gilberto Campos Guimarães Filho1, Ana Luiza Lima Sousa1, Thiago de Souza Veiga Jardim1
1Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
Insights
Blood pressure control improved in Brazilian hypertension patients, but lifestyle risk factors worsened, leading to increased cardiovascular events. This highlights the ongoing challenge of managing hypertension effectively.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertension is a significant public health issue due to its high prevalence, poor control rates, and associated cardiovascular complications.
- Effective management of hypertension is crucial for reducing morbidity and mortality.
Purpose of the Study:
- To evaluate blood pressure (BP) control and cardiovascular outcomes in patients at a Hypertension and Diabetes Reference Center in Brazil.
- To assess changes in BP control and risk factors over a five-year follow-up period.
Main Methods:
- A population-based study involving 1,298 adult patients regularly monitored at the center.
- Comparison of patient data at admission and after an average five-year follow-up.
- Assessment of demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes.
Main Results:
- Over time, physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight significantly increased.
- Stroke and myocardial revascularization rates increased, while chronic renal failure decreased.
- Blood pressure control improved significantly (from 29.6% to 39.6%), with 72 deaths, 91.7% from cardiovascular causes.
Conclusions:
- Despite improved blood pressure control rates, key cardiovascular risk factors deteriorated.
- The study indicates a complex interplay between improved BP management and worsening lifestyle factors, impacting cardiovascular outcomes.
Background:
Hypertension is a public health problem, considering its high prevalence, low control rate and cardiovascular complications.
Objective:
Evaluate the control of blood pressure (BP) and cardiovascular outcomes in patients enrolled at the Reference Center for Hypertension and Diabetes, located in a medium-sized city in the Midwest Region of Brazil.
Methods:
Population-based study comparing patients enrolled in the service at the time of their admission and after an average follow-up of five years. Participants were aged ≥ 18 years and were regularly monitored at the Center up to 6 months before data collection. We assessed demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes.
Results:
We studied 1,298 individuals, predominantly women (60.9%), and with mean age of 56.7 ± 13.1 years. Over time, there was a significant increase in physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight. As for cardiovascular outcomes, we observed an increase in stroke and myocardial revascularization, and a lower frequency of chronic renal failure. During follow-up, there was significant improvement in the rate of BP control (from 29.6% to 39.6%; p = 0.001) and 72 deaths, 91.7% of which were due to cardiovascular diseases.
Conclusion:
Despite considerable improvements in the rate of BP control during follow-up, risk factors worsened and cardiovascular outcomes increased.
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