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Updated: Apr 12, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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Oncolytic viruses: From bench to bedside with a focus on safety

Pascal R A Buijs1, Judith H E Verhagen, Casper H J van Eijck

  • 1a Department of Surgery; Erasmus MC; University Medical Center ; Rotterdam , The Netherlands.

Human Vaccines & Immunotherapeutics
|May 22, 2015
PubMed

Keywords:
CAR, Coxsackie Adenovirus receptorCD, cytosine deaminaseCEA, carcinoembryonic antigenCVA, Coxsackievirus type ADAF, decay accelerating factorDNA, DNAEEV, extracellular enveloped virusEGF, epidermal growth factorEGF-R, EGF receptorEMA, European Medicines AgencyFDA, Food and Drug AdministrationGBM, glioblastoma multiformeGM-CSF, granulocyte-macrophage colony-stimulating factorHA, hemagglutininHAdV, Human (mast)adenovirusHER2, human epidermal growth factor receptor 2HSV, herpes simplex virusICAM-1, intercellular adhesion molecule 1IFN, interferonIRES, internal ribosome entry siteKRAS, Kirsten rat sarcoma viral oncogene homologKb, kilobase pairsMeV, Measles virusMuLV, Murine leukemia virusNDV, Newcastle disease virusNIS, sodium/iodide symporterNSCLC, non-small cell lung carcinomaOV, oncolytic virusPEG, polyethylene glycolPKR, protein kinase RPV, Polio virusRCR, replication competent retrovirusRCT, randomized controlled trialRGD, arginylglycylaspartic acid (Arg-Gly-Asp)RNA, ribonucleic acidRb, retinoblastomaSVV, Seneca Valley virusTGFα, transforming growth factor αVGF, Vaccinia growth factorVSV, Vesicular stomatitis virusVV, Vaccinia viruscancercrHAdV, conditionally replicating HAdVdsDNA, double stranded DNAdsRNA, double stranded RNAenvironmenthIFNβ, human IFN βimmunotherapymORV, Mammalian orthoreovirusmORV-T3D, mORV type 3 DearingoHSV, oncolytic HSVoncolytic virotherapyoncolytic virusrdHAdV, replication-deficient HAdVreviewsafetysheddingssRNA, single stranded RNAtk, thymidine kinase

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