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Updated: Apr 12, 2026

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Case Study: Diffuse Large B-Cell Lymphoma Arising in Ovarian Mature Cystic Teratoma
Aoife Maguire1, Giuseppa Castriciano, Jan Walker
1Department of Histopathology (A.M., G.C., J.W., M.J., E.G., R.F.), Cancer Molecular Diagnostics (K.M., F.Q.) Departments of Oncology (N.O.) Haematology and Cancer Molecular Diagnostics (E.V.), St. James's Hospital, Dublin, Ireland.
Abstract:
We describe an unexpected finding of diffuse large B-cell lymphoma associated with mature cystic teratoma of the ovary. A 68-yr-old woman with a complex left ovarian cystic mass on imaging underwent bilateral salpingo-oophorectomy, lymphadenectomy, appendicectomy, and omentectomy. Histopathologic examination revealed nodules of malignant non-Hodgkin lymphoma within the teratoma. A diagnosis of diffuse large B-cell lymphoma, germinal center cell subtype by Hans criteria was made after immunostaining and molecular studies. The patient was treated with R-CHOP chemotherapy and remains disease-free at 14-mo follow-up.
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