Related Experiment Videos
Hb Bruxelles: alpha 2A beta (2)41 or 42(C7 or CD1)Phe deleted
Y Blouquit1, J Bardakdjian, D Lena-Russo
1INSERM U.91, Hôpital Henri Mondor, Créteil, France.
Hemoglobin
|January 1, 1989
Abstract:
Hb Bruxelles is a new beta-globin variant producing severe congenital Heinz body anemia. It results from the deletion of one of the two adjacent phenylalanines, beta 41 or beta 42, presumably by frameshift mutagenesis. Its whole blood oxygen affinity is significantly lowered.