Draft genome sequences of 18 oral streptococcus strains that encode amylase-binding proteins
Amarpreet Sabharwal1, Yu-Chieh Liao2, Hsin-Hung Lin2
1Department of Oral Biology, University at Buffalo, State University of New York, Buffalo, New York, USA.
Genome Announcements
|May 23, 2015
Abstract:
A number of commensal oral streptococcal species produce a heterogeneous group of proteins that mediate binding of salivary α-amylase. This interaction likely influences streptococcal colonization of the oral cavity. Here, we present draft genome sequences of several strains of oral streptococcal species that bind human salivary amylase.
Related Concept Videos
01:27The Oral Microbiota
52
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
52
01:28Development of the Oral Microbiota
39
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
39