Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Oncogenic cell fate decision in breast epithelial cells I: growth factors and mechanisms.

Research square·2026

Same author

Complex Coronary Artery Bypass Grafting: Intraoperative Challenges and Surgical Strategies in Contemporary Practice.

Journal of clinical medicine·2026

Same author

The "floating" valve, a modified bioroot Bentall procedure.

Frontiers in cardiovascular medicine·2026

Same author

Cyclic peptide-based shear-thinning and self-healing hydrogels as injectable nanotherapeutics.

Biomaterials science·2026

Same author

Fractured Sternal Wires Post Coronary Surgery: A Cross-Sectional Study Examining Wire Configurations, Sternal Locations, and Breakage Sites.

The Annals of thoracic surgery·2026

Same author

From Last Resort to Standard of Care: The Evolution and Future of Transcatheter Aortic Valve Implantation.

Reviews in cardiovascular medicine·2026

Search research articles

Related Experiment Video

Updated: Apr 12, 2026

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Published on: March 19, 2013

Cardiac tissue engineering and regeneration using cell-based therapy.

Mohammad T Alrefai¹, Divya Murali², Arghya Paul²

¹Division of Cardiac Surgery, McGill University Health Center, Montreal, QC, Canada ; Division of Surgical Research, McGill University Health Center, Montreal, QC, Canada ; King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.

Stem Cells and Cloning : Advances and Applications

|May 23, 2015

Summary

This summary is machine-generated.

Stem cell therapy and tissue engineering offer new hope for treating heart disease, addressing irreversible damage beyond restoring blood flow. Research explores various stem cell types for cardiac repair, promising future clinical applications.

Keywords:

cardiac surgery cardiomyocytes cell sheet and tissue engineering heart heart failure myocardial ischemia organoids scaffolds stem cells

More Related Videos

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy

Published on: March 1, 2016

Preparation of Mesh-Shaped Engineered Cardiac Tissues Derived from Human iPS Cells for In Vivo Myocardial Repair

Preparation of Mesh-Shaped Engineered Cardiac Tissues Derived from Human iPS Cells for In Vivo Myocardial Repair

Published on: June 9, 2020

Related Experiment Videos

Last Updated: Apr 12, 2026

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Published on: March 19, 2013

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy

Published on: March 1, 2016

Preparation of Mesh-Shaped Engineered Cardiac Tissues Derived from Human iPS Cells for In Vivo Myocardial Repair

Preparation of Mesh-Shaped Engineered Cardiac Tissues Derived from Human iPS Cells for In Vivo Myocardial Repair

Published on: June 9, 2020

Area of Science:

Regenerative Medicine
Cardiovascular Research

Background:

Current heart disease treatments focus on restoring blood flow but do not repair irreversible myocardial damage.
Stem cell therapy and tissue engineering are emerging as promising strategies for treating cardiac conditions.

Purpose of the Study:

To review pioneering research in stem cell therapy and tissue engineering for heart disease.
To present key findings from allogeneic and autologous stem cell trials in cardiac treatment.

Main Methods:

Review of existing literature on stem cell therapy for cardiac conditions.
Analysis of clinical trial results using various stem cell sources.

Main Results:

Stem cell therapies show potential for treating acute ischemic myocardial injury and chronic heart failure.
Trials include embryonic, bone marrow-derived, adipose-derived, and resident cardiac stem cells.

Conclusions:

Stem cell therapy and tissue engineering are advancing treatment options for heart disease.
These technologies are expected to become integral to cardiac disease management in the near future.