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Updated: Apr 12, 2026

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
A novel reporting system to improve accuracy in appendicitis imaging.
Benjamin D Godwin1, Frederick T Drake, Vlad V Simianu
11 Department of Radiology, University of Washington, 1959 NE Pacific St, UW Mailbox 357115, Seattle, WA 98195.
A standardized reporting system for appendicitis imaging improved diagnostic accuracy. This system, using objective findings and a certainty score, helped reduce indeterminate CT results for appendicitis.
Area of Science:
- Radiology
- Medical Imaging
- Diagnostic Accuracy
Background:
- Appendicitis diagnosis relies heavily on imaging, but interpretation can be subjective.
- Standardized reporting aims to improve consistency and accuracy in radiologic assessments.
Purpose of the Study:
- To evaluate if a standardized radiologic reporting system enhances diagnostic accuracy for appendicitis.
- To assess the utility of objective imaging findings and a certainty score in appendicitis diagnosis.
Main Methods:
- Developed a standardized reporting system with objective appendicitis imaging findings and a 1-5 certainty score.
- Four radiologists retrospectively reviewed 96 preoperative CT scans using the system.
- Compared imaging findings and certainty scores with final pathology, using odds ratios (ORs) and AUC.
Main Results:
- Appendicitis was confirmed in 71 of 89 visualized appendices (80%).
- Key imaging findings included appendiceal diameter, fat stranding, and mucosal hyperenhancement (all significant ORs).
- In indeterminate cases, the system correctly assigned high certainty scores (4 or 5) to 75% of appendicitis cases (AUC = 0.90).
Conclusions:
- Standardized reporting of objective findings correlates well with appendicitis pathology.
- This system may reduce the frequency of indeterminate CT findings for appendicitis.
- Prospective evaluation in clinically suspected appendicitis cases is ongoing.
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