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Updated: Apr 12, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Telemedicine framework using case-based reasoning with evidences
A Sene1, B Kamsu-Foguem2, P Rumeau3
1Laboratoire Génie de Production (LGP), EA 1905, ENIT-INPT, Université de Toulouse, 47 avenue d'Azereix, BP 1629, 65016 Tarbes Cedex, France; Laboratoire de Gérontechnologie La Grave, CHU Toulouse/Gérontopôle/UMR 1027 Inserm-Université Toulouse 3, Hôpital La Grave, Place Lange, TSA 60033, 31059 Toulouse Cedex 9, France.
Abstract:
Telemedicine is the medical practice of information exchanged from one location to another through electronic communications to improve the delivery of health care services. This research article describes a telemedicine framework with knowledge engineering using taxonomic reasoning of ontology modeling and semantic similarity. In addition to being a precious support in the procedure of medical decision-making, this framework can be used to strengthen significant collaborations and traceability that are important for the development of official deployment of telemedicine applications. Adequate mechanisms for information management with traceability of the reasoning process are also essential in the fields of epidemiology and public health. In this paper we enrich the case-based reasoning process by taking into account former evidence-based knowledge. We use the regular four steps approach and implement an additional (iii) step: (i) establish diagnosis, (ii) retrieve treatment, (iii) apply evidence, (iv) adaptation, (v) retain. Each step is performed using tools from knowledge engineering and information processing (natural language processing, ontology, indexation, algorithm, etc.). The case representation is done by the taxonomy component of a medical ontology model. The proposed approach is illustrated with an example from the oncology domain. Medical ontology allows a good and efficient modeling of the patient and his treatment. We are pointing up the role of evidences and specialist's opinions in effectiveness and safety of care.
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