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IVIg for relapsing-remitting multiple sclerosis: promises and uncertainties

Jagadeesh Bayry1, Hans-Peter Hartung2, Srini V Kaveri1

  • 1Institut National de la Santé et de la Recherche Médicale Unité 1138, Paris F-75006, France; Centre de Recherche des Cordeliers, Equipe - Immunopathology and Therapeutic Immunointervention, Paris F-75006, France; Sorbonne Universités, UPMC University Paris 06, UMR S 1138, Paris F-75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris F-75006, France; International Associated Laboratory IMPACT (Institut National de la Santé et de la Recherche Médicale, France - Indian Council of Medical Research, India), National Institute of Immunohematology, Mumbai 400012, India.

Trends in Pharmacological Sciences
|May 25, 2015
PubMed

Despite promising clinical trials, intravenous immunoglobulin (IVIg) therapy in relapsing-remitting multiple sclerosis (MS) has met with uncertainties that might be attributed to small patient cohorts, heterogeneity in the patients, dose of IVIg, or the duration and window of treatment.

Keywords:
IVIgautoimmunitybiomarkersimmunotherapyinflammationmultiple sclerosis

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