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DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner

Geoffrey O Gillard1, Brian Collette1, John Anderson1

  • 1Biogen, Inc., 115 Broadway, Cambridge, MA 02142, USA.

Journal of Neuroimmunology
|May 26, 2015
PubMed

Keywords:
CytokineDimethyl fumarate (DMF)Monoethyl fumarate (MEF)Monomethyl fumarate (MMF)Nuclear factor (erythroid-derived 2)-like 2 (Nrf2)Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)

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