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Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

56
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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Bacterial Phylum Verrucomicrobiota01:26

Bacterial Phylum Verrucomicrobiota

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The phylum Verrucomicrobiota comprises at least four characterized orders, with most species classified within the order Verrucomicrobiotales. Members of this phylum are either aerobic or facultatively aerobic, with the ability to ferment sugars. A notable exception is the genus Methylacidiphilum, which consists of aerobic methanotrophs. Additionally, some Verrucomicrobiota establish symbiotic relationships with protists. These bacteria are widely distributed across various environments,...
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Regulation of Bacterial Virulence01:28

Regulation of Bacterial Virulence

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Pathogenic bacteria employ a range of regulatory mechanisms to modulate the expression of virulence genes in response to environmental and host-derived signals. These mechanisms ensure that virulence factors are expressed only under favorable conditions, thereby optimizing infection and survival strategies.Mechanisms of Virulence RegulationKey regulatory strategies include:Two-Component Systems: These consist of a membrane-bound sensor kinase and a cytoplasmic response regulator. Environmental...
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Human Virome01:26

Human Virome

42
The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible...
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Cholera01:25

Cholera

81
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
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Reservoir of Infection01:30

Reservoir of Infection

53
Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
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Updated: Apr 12, 2026

Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms
03:29

Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms

Published on: May 31, 2024

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Vibriosis.

J Michael Janda1, Anna E Newton2, Cheryl A Bopp3

  • 1Department of Public Health, Alameda County Public Health Laboratory, 1000 Broadway, Suite 500, Oakland, CA 94607, USA.

Clinics in Laboratory Medicine
|May 26, 2015
PubMed
Summary
This summary is machine-generated.

Vibriosis, caused by Vibrio bacteria from marine environments, is increasing in the US. New laboratory methods improve the detection and identification of these potentially severe infections, including cholera.

Keywords:
AquaticCholeraMarineSeafoodV vulnificusVibrioVibriosis

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Area of Science:

  • Marine microbiology
  • Infectious diseases

Background:

  • Vibriosis encompasses diverse infections from marine Vibrio bacteria.
  • Illnesses range from mild to severe, such as cholera and necrotizing fasciitis.
  • Exposure occurs via marine contact or consuming contaminated shellfish, particularly oysters.

Purpose of the Study:

  • To highlight the increasing incidence of Vibrio infections in the US.
  • To address the underreporting of these infections due to diagnostic challenges.
  • To introduce recent advancements in laboratory detection and identification.

Main Methods:

  • Review of Vibrio-related illnesses and their sources.
  • Discussion of diagnostic limitations in clinical and laboratory settings.
  • Overview of emerging laboratory technologies for Vibrio detection.

Main Results:

  • Vibrio infections are rising in the United States.
  • Underreporting is linked to clinical and laboratory detection gaps.
  • New tests, media, and molecular systems enhance Vibrio identification.

Conclusions:

  • Improved clinical recognition and laboratory diagnostics are crucial for accurate Vibriosis reporting.
  • Advancements in detection methods are vital for managing Vibrio infections.
  • Enhanced surveillance and diagnostics can mitigate the impact of these marine-borne pathogens.