Metal nanoparticles: a theranostic nanotool against cancer

Harshita Sharma1, Pawan K Mishra2, Sushama Talegaonkar3

  • 1Department of Pharmaceutics, ISF College of Pharmacy, Moga, Punjab, India; Department of Pharmaceutics, Jamia Hamdard, New Delhi, India.

Insights

Metal nanoparticles offer a promising new approach to cancer treatment by combining diagnosis and therapy. These agents, including iron, gold, and silver nanoparticles, show potential for enhanced anticancer strategies.

Area of Science:

  • Oncology
  • Nanotechnology
  • Materials Science

Background:

  • Conventional cancer therapies present significant limitations and side effects.
  • There is a critical need for innovative and more effective anticancer strategies.
  • Theranostics, integrating diagnosis with targeted therapy, is an emerging field.

Purpose of the Study:

  • To explore the potential of metal nanoparticles as theranostic agents for cancer treatment.
  • To highlight the dual role of metal nanoparticles in cancer diagnosis and therapy.
  • To review various metals with anticancer potential in nanoparticle form.

Main Methods:

  • Review of existing literature on metal nanoparticles in cancer theranostics.
  • Analysis of the inherent and surface-modified properties of metal nanoparticles for anticancer activity.
  • Examination of the diagnostic and therapeutic applications of functionalized metal nanoparticles.

Main Results:

  • Metal nanoparticles, including iron, gold (Au), silver (Ag), zinc (Zn), and titanium, demonstrate significant potential as anticancer agents.
  • Surface modifications can enhance the inherent anticancer efficacy of these nanoparticles.
  • Metal nanoparticles effectively function as dual-action agents for both cancer diagnosis and therapy.

Conclusions:

  • Metal nanoparticles represent a highly promising platform for advancing cancer theranostics.
  • Their ability to combine diagnostic and therapeutic functions offers a significant advantage over conventional treatments.
  • Further research into metal nanoparticle-based theranostics could lead to improved cancer patient outcomes.