Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

2.3K
The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte...
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Capillary flow-driven paper-based microfluidic sensor for NDMA detection in water.

Lab on a chip·2026
Same author

Facility-wide assessment of occupational exposure to dust, noise, and formaldehyde.

Journal of exposure science & environmental epidemiology·2026
Same author

Integrated Magnetophoretic-Electrochemical platforms for portable detection of HER2 in breast cancer diagnosis.

Biosensors & bioelectronics·2026
Same author

Smartphone-Based Peptide Nucleic Acid (PNA) Probe-Assisted Potentiometric Biosensor for Point-of-Care Testing of SARS-CoV-2 Nucleic Acid.

Analytical chemistry·2026
Same author

Integrating the physical environment into Alzheimer's disease and Alzheimer's disease related dementias research: A Gateway Exposome Coordinating Center (GECC) agenda on gaps and priorities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Detection of Aerosolized Protein Using a Condensation Growth Tube Coupled with an Electrochemical Immunoassay on Screen-Printed Carbon Electrodes.

Analytical chemistry·2026

Related Experiment Video

Updated: Apr 11, 2026

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
09:51

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

Published on: September 19, 2025

604

Multiplexed paper analytical device for quantification of metals using distance-based detection.

David M Cate1, Scott D Noblitt, John Volckens

  • 1School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado 80523, USA. John.Volckens@colostate.edu Chuck.Henry@colostate.edu.

Lab on a Chip
|May 27, 2015
PubMed
Summary

A novel paper-based sensor visually quantifies airborne metals like nickel (Ni), copper (Cu), and iron (Fe). This cost-effective method offers rapid, instrument-free analysis for environmental and occupational health monitoring.

More Related Videos

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
10:31

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores

Published on: December 6, 2015

28.8K
Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

8.2K

Related Experiment Videos

Last Updated: Apr 11, 2026

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
09:51

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

Published on: September 19, 2025

604
Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
10:31

Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores

Published on: December 6, 2015

28.8K
Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
05:35

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography

Published on: January 17, 2020

8.2K

Area of Science:

  • Environmental Science
  • Analytical Chemistry
  • Materials Science

Background:

  • Metal-containing aerosols pose significant health risks.
  • Current methods for metal quantification are costly and time-consuming.
  • Need for accessible, rapid metal detection techniques.

Purpose of the Study:

  • Develop a simple, low-cost method for quantifying airborne metals (Ni, Cu, Fe).
  • Utilize microfluidic paper-based analytical devices (µPADs) with distance-based detection.
  • Enable visual, instrument-free quantification.

Main Methods:

  • Fabrication of paper-based sensors using a distance-based detection motif.
  • Colorimetric quantification of Ni, Cu, and Fe based on reaction distance.
  • Development of single-analyte and multiplexed detection capabilities.
  • Extension of dynamic range using inkjet-printed reagent gradients.

Main Results:

  • Achieved low detection limits for individual metals: Ni (0.1 μg), Cu (0.1 μg), Fe (0.05 μg).
  • Demonstrated multiplexed detection with limits: Ni (1 μg), Cu (5 μg), Fe (1 μg).
  • Validated method with certified welding fume samples, showing good agreement with gravimetric analysis.
  • Confirmed analyte selectivity against common interferences.

Conclusions:

  • The developed µPADs offer a simple, visual, and cost-effective approach for airborne metal quantification.
  • Distance-based detection eliminates the need for optical instrumentation, enhancing accessibility.
  • This technology holds promise for field monitoring of environmental and occupational exposures to metals.