Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

34.1K
Overview
34.1K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

207
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
207
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

1.6K
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.6K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.7K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.7K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

5.0K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
5.0K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acupuncture for benign prostatic hyperplasia in the elderly: A systematic review of acupoints.

Medicine·2025
Same author

lncRNA AGAP2-AS1 Facilitates Tumorigenesis and Ferroptosis Resistance through SLC7A11 by IGF2BP2 Pathway in Melanoma.

Computational and mathematical methods in medicine·2022
Same author

Protective Effect of Schisandrin on CORT-Induced PC12 Depression Cell Model by Inhibiting Cell Apoptosis In Vitro.

Applied bionics and biomechanics·2022
Same author

Protective effect of isopsoralen on UVB-induced injury in HaCaT cells via the ER and p38MAPK signaling pathways.

Journal of food biochemistry·2022
Same author

Isoastilbin inhibits neuronal apoptosis and oxidative stress in a rat model of ischemia-reperfusion injury in the brain: Involvement of SIRT1/3/6.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University·2021
Same author

P-FN12, an H4R-Based Epitope Vaccine Screened by Phage Display, Regulates the Th1/Th2 Balance in Rat Allergic Rhinitis.

Molecular therapy. Methods & clinical development·2018

Related Experiment Video

Updated: Apr 11, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

32.5K

[Allergic inflammation in respiratory system].

Lifeng An, Yanshu Wang, Lin Li

    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
    |May 28, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Allergic diseases like asthma involve inflammatory cell activation, releasing mediators that affect target cells and nerves, causing symptoms. This review covers inflammatory cells, superantigens, small molecules, nerve fibers, and genetic factors in allergic inflammation.

    More Related Videos

    Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
    06:08

    Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

    Published on: September 22, 2023

    2.9K
    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
    10:39

    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

    Published on: April 16, 2019

    8.3K

    Related Experiment Videos

    Last Updated: Apr 11, 2026

    Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
    11:54

    Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

    Published on: January 21, 2018

    32.5K
    Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
    06:08

    Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

    Published on: September 22, 2023

    2.9K
    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
    10:39

    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

    Published on: April 16, 2019

    8.3K

    Area of Science:

    • Immunology
    • Pathophysiology
    • Molecular Biology

    Background:

    • Allergic diseases, including asthma and allergic rhinitis, share common pathophysiological pathways.
    • Disruptions in endogenous and exogenous inflammatory mechanisms trigger disease onset.

    Purpose of the Study:

    • To review research progress in allergic inflammatory diseases.
    • To elucidate the mechanisms underlying allergic inflammation.

    Main Methods:

    • Literature review focusing on key aspects of allergic inflammation.
    • Analysis of research on inflammatory cells, superantigens, small molecules, nerve fibers, and genetic factors.

    Main Results:

    • Inflammatory cell activation is central, involving cytokine and mediator release.
    • Sensory nerve fibers and target cells are activated, leading to organ-specific effects and clinical symptoms.
    • Research progress spans inflammatory cells, staphylococcus aureus superantigen, small molecules (cytokines, mediators, lipids), nerve fibers, effect cells, and genetic/epigenetic factors.

    Conclusions:

    • Understanding the complex interplay of these factors is crucial for managing allergic diseases.
    • This review provides a comprehensive overview of current research in allergic inflammation.