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Updated: Apr 11, 2026

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Measurement of Chitinase Activity in Biological Samples
Published on: August 22, 2019
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Effects of chitin and its derivatives on human cancer cells lines
M Bouhenna1, R Salah1, R Bakour2
1Unité de Recherche URIE, Ecole Nationale Polytechnique, 10 Avenue Pasteur El Harrach, Alger, Algeria.
Abstract:
The present study is focused on the effect of chitin derivatives against human cancer cell lines RD and Hep2. As an outcome from this research, chitin was cytotoxic at IC50 = 400 μg/ml and 200 μg/ml against Hep2 cells and RD cells lines, respectively. Irradiated chitin had an IC50 value of 450 μg/ml for Hep2 and an IC50 of 200 μg/ml for RD. The lowest IC50 is attributed to chitosan, 300 μg/ml in Hep2 and 190 μg/ml in RD.

