Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phenotypic profiles for anticancer drug responses using tumor spheroids.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Development of a customizable vascularization strategy using a modular microfluidic platform for fibroblast-free vascularized tissue.

Materials today. Bio·2026
Same author

ctDNA for Prognostication and Monitoring in Patients with Metastatic Endometrial Carcinoma Treated with Olaparib: Validation in the GINECO-UTOLA Trial.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

Factors of bias in spheroid-based drug screening: Fabrication method, spheroid size, and cell viability.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2025
Same author

Confocal Absorbance-Activated Droplet Sorting (cAADS) for Enzyme Engineering.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Targeting CDK4/6 in Cancer: Molecular Docking and Cytotoxic Evaluation of <i>Thottea siliquosa</i> Root Extract.

Biomedicines·2025

Related Experiment Video

Updated: Apr 11, 2026

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays
11:03

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays

Published on: March 9, 2021

6.9K

Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays.

Jiseok Lim, Ouriel Caen, Jérémy Vrignon

  • 1Max Planck Institute for Biophysical Chemistry , Am Fassberg 11, 37077 Goettingen, Germany.

Biomicrofluidics
|May 28, 2015
PubMed
Summary
This summary is machine-generated.

This study introduces a novel droplet-based microfluidic system for high-throughput emulsion production. The innovative pipette-and-play device enables simultaneous manipulation of 10 distinct phases on a single layer, enhancing biochemical and material science applications.

More Related Videos

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
10:00

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing

Published on: May 23, 2018

18.5K
Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.8K

Related Experiment Videos

Last Updated: Apr 11, 2026

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays
11:03

Particle Templated Emulsification enables Microfluidic-Free Droplet Assays

Published on: March 9, 2021

6.9K
An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
10:00

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing

Published on: May 23, 2018

18.5K
Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.8K

Area of Science:

  • Microfluidics
  • Biochemistry
  • Material Science

Background:

  • Droplet-based microfluidic technologies are essential for high-throughput applications.
  • Existing systems for monodisperse emulsion production have limitations, including single-phase manipulation and complex multi-layer fabrication.

Purpose of the Study:

  • To present a novel pipette-and-play droplet microfluidic system.
  • To enable simultaneous manipulation of multiple disperse phases on a single-layer device.
  • To achieve high-throughput production of emulsions with complex chemical compositions.

Main Methods:

  • Development of a single-layer microfluidic device.
  • Integration of a pipette-and-play system for easy setup.
  • Utilizing aqueous flow rates up to 26 ml/h for emulsion generation.

Main Results:

  • The system successfully manipulates 10 different disperse phases simultaneously.
  • Achieved high-throughput emulsion production exceeding 110,000 drops/s.
  • Demonstrated multiplex capabilities by measuring enzyme kinetics with varying substrate concentrations.

Conclusions:

  • The developed microfluidic system overcomes limitations of previous technologies.
  • It offers a versatile and efficient platform for high-throughput emulsion production with complex compositions.
  • The system is suitable for diverse applications in biochemistry and material sciences, including kinetic studies.