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Updated: Apr 11, 2026

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
Published on: June 20, 2012
Orbitofrontal sulcal and gyrus pattern in human: an anatomical study
Thiago Pereira Rodrigues1, Mariana Athaniel Silva Rodrigues2, Daniel de Araújo Paz1
1Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Unlabelled:
The anatomical characterization of the orbitofrontal cortex in human is limited in literature instead of many functional and clinical studies involving it.
Objective:
Anatomically define the orbitofrontal region aiming to possible neurosurgical treatments and unify the scientific nomenclature as well.
Method:
We analyze eighty four human hemispheres using a surgical microscope. Then we chose four hemispheres and dissect them according to Klinger' technique.
Results:
We found five main sulcus: olfatory sulcus, orbital medial sulcus, orbital lateral sulcus, orbital transverse sulcus and orbital intermediate sulcus. These sulcus, excluding the intermediate sulcus, delimit five gyrus: rectus gurys, orbital medial gyrus, orbital anterior gyrus, orbital lateral gyrus and orbital posterior gyrus. The main sulcal configuration can be divided on four more frequently patterns.
Conclusion:
Orbitofrontal cortex is associated with many psychiatric disorders. Better anatomical and functional characterization of the orbitofrontal cortex and its connections will improve our knowledge about these diseases.
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