Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sleep changes in fasting rats.

G Dewasmes1, C Duchamp, Y Minaire

  • 1Centre National de la Recherche Scientifique Institut National de Recherche et de Sécurité, UMR 32, Strasbourg, France.

Physiology & Behavior
|August 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Time course of liver nitric oxide concentration in early septic shock by cecal ligation and puncture in rats.

Nitric oxide : biology and chemistry·2010
Same author

[The place of laparoscopy in the management of the patients with penetrating abdominal trauma].

Journal de chirurgie·2007
Same author

Environmental green chemistry as defined by photocatalysis.

Journal of hazardous materials·2007
Same author

Effect of fasting on the VO2-fh relationship in king penguins, Aptenodytes patagonicus.

American journal of physiology. Regulatory, integrative and comparative physiology·2004
Same author

Pattern of rapid-eye movement sleep episode occurrence after an immobilization stress in the rat.

Neuroscience letters·2004
Same author

Effects of a moderate nocturnal cold stress on daytime sleep in humans.

European journal of applied physiology·2003
Same journal

Apelin receptor antagonist (ML221) facilitates memory reconsolidation in novel object recognition task.

Physiology & behavior·2026
Same journal

50-kHz ultrasonic vocalization subtypes emitted by female rats anticipating same-sex social interaction.

Physiology & behavior·2026
Same journal

Sex-dependent behavioral and prefrontal BDNF mRNA responses to extinction training and short-term citalopram after fear conditioning in rats.

Physiology & behavior·2026
Same journal

Social instability alters the topography of adolescent and adult social behavior and amygdala function.

Physiology & behavior·2026
Same journal

Mitochondrial remodeling in obesity: mechanistic links to impaired energy metabolism and therapeutic perspectives.

Physiology & behavior·2026
Same journal

Orexinergic and opioidergic receptors interaction in the dentate gyrus of the hippocampus on modulation of formalin-induced inflammatory pain responses in the rat.

Physiology & behavior·2026
See all related articles

Prolonged food deprivation in rats alters sleep patterns. Initially, sleep-wake cycles remain stable, but later stages show increased wakefulness and suppressed sleep, shifting nocturnal rats to diurnal activity.

Area of Science:

  • Neuroscience
  • Physiology
  • Animal Behavior

Background:

  • Prolonged food deprivation induces distinct metabolic phases in rodents.
  • Understanding sleep-wake dynamics during fasting is crucial for metabolic adaptation.
  • Previous studies have not fully detailed sleep changes across all fasting phases.

Purpose of the Study:

  • To investigate the impact of prolonged food deprivation on sleep-wake states in rats.
  • To correlate metabolic changes during fasting with alterations in sleep architecture.
  • To examine the adaptive strategies of sleep mechanisms in response to starvation.

Main Methods:

  • Studied sleep-wake patterns (wakefulness, slow-wave sleep, paradoxical sleep) in rats over 24-hour periods.
  • Compared fed conditions with prolonged food deprivation (2-3 weeks).

Related Experiment Videos

  • Analyzed changes across three successive metabolic phases of fasting.

    • Main Results:

    • During fasting phase II (protein sparing), sleep-wake proportions were unchanged, but daily rhythms amplitude decreased.
    • In fasting phase III (increased protein use), wakefulness significantly increased, suppressing slow-wave and paradoxical sleep.
    • Fasting induced a shift from nocturnal to diurnal activity patterns in rats.

    Conclusions:

    • Food deprivation significantly alters sleep regulation, impacting homeostatic and cyclic components.
    • Sleep changes reflect an adaptive strategy to conserve energy and enhance alertness during starvation.
    • Metabolic phase transitions during fasting correlate with distinct sleep-wake state modifications.