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Parallel donor genotyping for 46 selected blood group and 4 human platelet antigens using high-throughput MALDI-TOF

Stefan Meyer1, Nadine Trost, Beat M Frey

  • 1Department of Molecular Diagnostics and Research (MOC), Swiss Red Cross Blood Transfusion Service Zurich, Rütistrasse 19, 8952, Schlieren, Switzerland.

Methods in Molecular Biology (Clifton, N.J.)
|May 31, 2015
PubMed

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Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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