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Related Experiment Video

Updated: Apr 11, 2026

Monitoring Acupuncture Effects on Human Brain by fMRI
09:55

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Acupuncture-brain interactions as hypothesized by mood scale recordings.

Helmut Acker1, Claudia Schmidt-Rathjens2, Till Acker3

  • 1Forschungsinstitut für Notfallmedizin und Gesundheit, Dortmund, Germany; Institute für Physiologie, Universität Duisburg-Essen, Essen, Germany.

Medical Hypotheses
|May 31, 2015
PubMed
Summary

Acupuncture effectively improved mood and reduced pain in chronic conditions by influencing brain activity. Mood scales proved sensitive for tracking these acupuncture-brain interactions over time.

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Area of Science:

  • Neuroscience
  • Integrative Medicine
  • Psychiatry

Background:

  • Mood scales can assess psychological states.
  • Acupuncture is used for chronic conditions, but its brain effects require further study.
  • Chronic pain and burnout are associated with negative mood states.

Purpose of the Study:

  • Introduce mood scales as a tool to evaluate acupuncture's impact on brain function.
  • Investigate acupuncture's effects on mood and EEG in burnout and chronic pain patients.
  • Explore correlations between pain intensity, mood changes, and physiological responses.

Main Methods:

  • Applied traditional acupuncture points to patients with burnout (n=10) and chronic pain (n=22).
  • Utilized mood scales to measure positive and negative affect.
  • Recorded electroencephalogram (EEG) to observe brainwave changes during acupuncture needle rotation.

Main Results:

  • Acupuncture significantly improved positive mood scales and reduced negative ones after 10 sessions.
  • Observed immediate suppression of unusual slow high-amplitude EEG waves in burnout patients, which returned after 1-1.5 years.
  • Both male and female chronic pain patients reported decreased pain intensity; female patients showed correlations between pain relief, mood, and heart rate.

Conclusions:

  • Mood scale recordings are a sensitive and specific tool for assessing individual acupuncture-brain interactions.
  • Acupuncture demonstrates direct effects on brain structures and mood regulation.
  • Sustained acupuncture treatment may be necessary to maintain therapeutic benefits.