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Updated: Dec 8, 2025

Transdermal Measurement of Glomerular Filtration Rate in Mice
Published on: October 21, 2018
[Microdialysis--a new method of monitoring of the transplanted cadaveric kidneys function]
Purpose:
To assess ischemia-reperfusion injury of renal allograft by microdialysis.
Design:
A pilot, single-center; prospective study.
Patients And Methods:
The study included 7 patients (4 males and 3 females, average age was 46.71 ± 6.53 years) after cadaveric kidney allograft transplantation (CKA) under general combined anaesthesia.
Conclusions:
Microdialysis provides an opportunity of continuous monitoring of metabolic changes in the tissue of transplanted kidney. The main advantage of the monitoring by microdialysis is an opportunity of early identifying of ischemia-reperfusion complications. Thus, early assessment of CKA by microdialysis can be for the improving of patient's treatment in the early post operative period. Further clinical studies must be done to define the role of microdialysis.

