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Published on: May 31, 2021
[Topical issues of food allergy diagnosis in pediatric practice]
Insights
Accurate diagnosis and timely management are crucial for children with food allergy (FA). A detailed medical history and clinical evaluation are the most reliable methods for identifying specific allergens in pediatric FA.
Area of Science:
- Pediatric Allergy and Immunology
- Clinical Diagnostics
- Public Health
Context:
- Food allergy (FA) in children is a significant public health concern, particularly in infancy.
- Effective management hinges on accurate and early diagnosis.
- Inappropriate dietary interventions can negatively impact child development and quality of life.
Purpose:
- To summarize current evidence-based approaches to diagnosing pediatric food allergy.
- To review European and Russian national consensus guidelines for FA diagnosis and management.
- To highlight the importance of clinical evaluation alongside laboratory testing.
Summary:
- Pediatric FA diagnosis typically involves clinical, laboratory, and anamnestic data.
- Current practices often overemphasize laboratory tests like specific IgE or skin prick tests.
- A thorough medical history and clinical presentation remain the most dependable methods for identifying causative allergens.
Impact:
- Promoting evidence-based diagnostic strategies for pediatric food allergy.
- Guiding clinicians towards optimal diagnostic pathways, balancing laboratory and clinical assessments.
- Improving the long-term health outcomes and quality of life for children with food allergies.
Abstract:
Food allergy (FA) in children, especially in infancy, is still a significant public health problem. The severity and prognosis of disease progression associated with FA considerably depends on the correct and early diagnostics of this pathology, as well as on the following management of a child. At the same time delayed elimination diet administration, unreasonable or overlong dietary intervention might have become abuse management of a patient and have a negative impact on the development of a child and reduce the quality of life. The article summarizes the current practical approaches to the diagnosis of FA based on evidence-based medicine and adopted European and Russian national consensus documents, as well as on our own experience of management of patients with this pathology. FA diagnosis in a child usually includes clinical laboratory tests and clarification of clinical and anamnestic data. Unfortunately, it is a fact that preference is given to laboratory methods for diagnosis based on specific IgE determination or skin samples. However, the basis for cause-significant allergen identifying is detecting detailed medical history and clinical picture of a disease which still appears to be the most reliable tool for FA diagnosis.
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