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Updated: Apr 11, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
Paraneoplastic cutaneous lupus secondary to esophageal squamous cell carcinoma
Thoyaja Koritala1, Joseph Tworek1, Brian Schapiro1
11 Department of Internal Medicine, Mayo Clinic, Fairmont, MN, USA ; 2 Department of Pathology, 3 Huron Gastroenterology, St. Joseph Mercy Hospital, Ypsilanti, MI, USA.
Abstract:
Sporadic subacute cutaneous lupus erythematosus (SCLE) in an elderly man does not fit a typical demographic for the disease process. Using the McLean's criteria we were able to establish a temporal relationship between the patient's diagnosis of esophageal squamous cell carcinoma (SCC) and his dermatosis, both of which responded to cytotoxic chemotherapy. The clinical presentation and progression of the clinical illness is supportive of a very unusual and not previously reported paraneoplastic SCLE secondary to esophageal SCC.
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